HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → Methanesulfonic acid 2-(5-bromo-benzothiazol-2-yl)-ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Methanesulfonyl chloride | HCID 31297 | — |
| Edukt | 5-Bromo-2-benzothiazoleethanol | HCID 21980060 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | Methanesulfonic acid 2-(5-bromo-benzothiazol-2-yl)-ethyl ester | HCID 21041502 | — |
Reaktionsschritte
To a mixture of 2-(5-bromo-benzothiazol-2-yl)-ethanol (0.94 g, 3.6 mmol) in 10 mL CH2Cl2, Et3N (0.99 g, 9.8 mmol), was added methanesulfonyl chloride (0.46 g, 4.0 mmol) dropwise at room temperature. The reaction was worked up by concentrating under vacuum and then used in the next step, Example 1C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08106088B2 |
| Quelldatensatz | uspto-grants-2012_01 |
| ORD ID | ord-e7dcb545557e41e8b09838c68bacf468 |
| Quellennotiz | uspto-grants-2012_01 |