HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Phenylpiperidine → [(1R,2S)-1-Benzyl-2-hydroxy-3-(4-phenyl-piperidin-1-yl)-propyl]-carbamic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Phenylpiperidine | HCID 69873 | — |
| Edukt | erythro-N-Boc-D-phenylalanine epoxide | HCID 11357515 | — |
| Produkt | [(1R,2S)-1-Benzyl-2-hydroxy-3-(4-phenyl-piperidin-1-yl)-propyl]-carbamic acid tert-butyl ester | HCID 66703612 | — |
Reaktionsschritte
Using general procedure 1 and purification method E with [(1R)-1-{(2R)-oxiran-2-yl}-2-phenyl-ethyl]carbamic acid tert-butylester (0.10 g, 0.38 mmol) and 4-phenyl-piperidine (0.122 g, 0.76 mmol) gives the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08106090B2 |
| Quelldatensatz | uspto-grants-2012_01 |
| ORD ID | ord-54ea1127c618433295f4bf6725ef2980 |
| Quellennotiz | uspto-grants-2012_01 |