erythro-N-Boc-D-phenylalanine epoxide → [(1R,2S)-3-Benzotriazol-2-yl-1-benzyl-2-hydroxy-propyl]-carbamic acid tert-butyl ester

Beteiligte Stoffe

Reaktionsschritte

Using general procedure 4 and purification method E (elute with isocratic 20% ethyl acetate/hexanes in this case) with [(1R)-1-{(2R)-oxiran-2-yl}-2-phenyl-ethyl]carbamic acid tert-butylester (0.25 g, 0.95 mmol) and 1,2,3-benzotriazole (0.136 g, 1.14 mmol) gives the title compound.

Herkunft & Nachweise