5-Chloronicotinic acid → (1S,2S,5R)-5-Chloro-N-[7-Methyl-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-nicotinamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	5-Chloronicotinic acid	HCID 247986	—
Edukt	[(1S,2S,5R)-2-aminomethyl-7-methyl-3-aza-bicyclo[3.3.0]oct-3-yl]-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone	HCID 59411601	—
Produkt	(1S,2S,5R)-5-Chloro-N-[7-Methyl-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-nicotinamide	HCID 25154297	—

Reaktionsschritte

prepared by reaction of [(1S,2S,5R)-2-aminomethyl-7-methyl-3-aza-bicyclo[3.3.0]oct-3-yl]-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 5-chloro-nicotinic acid.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08106215B2
Quelldatensatz	uspto-grants-2012_01
ORD ID	ord-82c65849fddb4b0787acc25e39acd156
Quellennotiz	uspto-grants-2012_01