HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(2-Morpholin-4-ylethoxy)benzeneboronic acid, pinacol ester → 3-(2,6-Dichloro-benzyloxy)-5-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-pyridin-2-ylamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(2-Morpholin-4-ylethoxy)benzeneboronic acid, pinacol ester | HCID 4625910 | — |
| Edukt | 3-(2,6-Dichlorobenzyloxy)-5-bromopyridin-2-amine | HCID 21111487 | — |
| Produkt | 3-(2,6-Dichloro-benzyloxy)-5-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-pyridin-2-ylamine | HCID 10254297 | — |
Reaktionsschritte
3-(2,6-Dichloro-benzyloxy)-5-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-pyridin-2-ylamine was prepared from 5-bromo-3-(2,6-dichloro-benzyloxy)-pyridin-2-ylamine (example I(a)) and 4-{2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-ethyl}-morpholine (prepared in part 1) following procedure 3 as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08106197B2 |
| Quelldatensatz | uspto-grants-2012_01 |
| ORD ID | ord-f3fd9ab8870d4a6aa11bd87ef76578f7 |
| Quellennotiz | uspto-grants-2012_01 |