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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 42601Erstellt: 23. Oktober 2026

1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- → 4,6-Diphenyl-2-(2-phthalimidoethyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine

https://huagongshe.com/de/reaction/42601

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)-HCID 11325—
Edukt4,6-diphenyl-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridineHCID 67014853—
Produkt4,6-Diphenyl-2-(2-phthalimidoethyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridineHCID 6701408331%

Reaktionsschritte

Following a similar procedure to that described in examples 6 and 7, but using 4,6-diphenyl-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine (obtained in example 2) instead of 4,6-bis(4-fluorophenyl)-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine and N-(2-bromoethyl)phthalimide instead of iodoethane, the title compound was obtained (yield: 31%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08536194B2
Quelldatensatzuspto-grants-2013_09
ORD IDord-04e337fc91c94a5184a2716db9c83c69
Quellennotizuspto-grants-2013_09