2-(3-Bromopropoxy)tetrahydro-2H-pyran → 5-(2-Methylsulfanylpyrimidin-4-yl)-2-[3-(tetrahydropyran-2-yloxy)propyl]-6-(3-trifluoromethylphenyl)pyrazolo[3,4-b]pyridine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-(3-Bromopropoxy)tetrahydro-2H-pyran	HCID 2777988	—
Edukt	5-[2-(methylsulfanyl)pyrimidin-4-yl]-6-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridine	HCID 67013869	—
Produkt	5-(2-Methylsulfanylpyrimidin-4-yl)-2-[3-(tetrahydropyran-2-yloxy)propyl]-6-(3-trifluoromethylphenyl)pyrazolo[3,4-b]pyridine	HCID 67014547	—

Reaktionsschritte

Following a similar procedure to that described in examples 6 and 7, but starting from 5-[2-(methylsulfanyl)pyrimidin-4-yl]-6-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridine (obtained in example 126) and 2-(3-bromopropoxy)tetrahydropyran, the title compound was obtained.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08536194B2
Quelldatensatz	uspto-grants-2013_09
ORD ID	ord-57193f1841a74ffb8d4227914efa1b74
Quellennotiz	uspto-grants-2013_09