HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzaldehyde → 1-(4-Cinnamoylphenyl)-4-(4-pyridyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzaldehyde | HCID 240 | — |
| Edukt | 1-(4-Acetylphenyl)-4-(4-pyridyl)piperazine | HCID 18357135 | — |
| Katalysator | Sodium Hydroxide | HCID 14798 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 1-(4-Cinnamoylphenyl)-4-(4-pyridyl)piperazine | HCID 53679170 | 50,3% |
Reaktionsschritte
A solution of 1-(4-acetylphenyl)-4-(4-pyridyl)piperazine (1.0 g), benzaldehyde (177 mg) and concentrated sodium hydroxide (3 drops) in ethanol (25 ml) was stirred at ambient temperature overnight to give a solid which was filtered, washed with ethanol and dried to give 1-(4-cinnamoylphenyl)-4-(4-pyridyl)piperazine (310 mg), m.p. 208-210° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06313127B1 |
| Quelldatensatz | uspto-grants-2001_11 |
| ORD ID | ord-0eaeb2ce37d845478c23552ddb4c4c49 |
| Quellennotiz | uspto-grants-2001_11 |