Thionyl Chloride → 2-Isopropyl-6-methylbenzylchloride

HRID 427512Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 427512
[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:5]=1[CH2:6]O)([CH3:3])[CH3:2].S(Cl)([Cl:15])=O>C(Cl)Cl>[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:5]=1[CH2:6][Cl:15])([CH3:3])[CH3:2]

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 18357444(2-Isopropyl-6-methylphenyl)methanol

Produkt 1

HCID 183574432-Isopropyl-6-methylbenzylchlorideAusbeute 96,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a solution of 2-isopropyl-6-methylbenzylalcohol (1.7 g, 10.4 mmol) in methylene chloride (20 ml) was added thionyl chloride (1.7 g, 14 mmol) and the reaction was stirred for 1 h. at room temperature. The solvent was evaporated under reduced pressure and the residue was filrated through silica gel using methylenechloride as eluent. The solvent was evaporated under reduced pressure to give 1.83 g (96%) of the title compound as an oil.

Aufarbeitung

  1. customThe solvent was evaporated under reduced pressure
  2. customThe solvent was evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-3aa176b262cf453884f4ed0481d82783
Quelldatensatz
uspto-grants-2001_11
Patentnummer
US06313137B1

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