HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Chloro-6,7-dimethoxy-4-quinazolinamine → Terazosin Hydrochloride Anhydrous
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Chloro-6,7-dimethoxy-4-quinazolinamine | HCID 90235 | — |
| Edukt | 1-(Tetrahydro-2-furoyl)piperazine | HCID 2734641 | — |
| Produkt | Terazosin Hydrochloride Anhydrous | HCID 44383 | 73,3% |
Reaktionsschritte
The procedures of Example 9 were followed except that Compound 3 from Example 1 (3.0 grams, 16.3 mmole) and 4-amino-2-chloro-6,7-bismethoxy quinazoline III (3.8 grams, 16.1 mmole) were reacted to obtain 5.0 grams of Terazosin hydrochloride (Yield: 73%). After alkalification, 4.7 grams of white Terazosin solid was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06313293B1 |
| Quelldatensatz | uspto-grants-2001_11 |
| ORD ID | ord-d20a34aff01f44b8851f5a208e4967f6 |
| Quellennotiz | uspto-grants-2001_11 |