4-(5-Cyano-1-methyl-3-indolyl)cyclohexanone → 4-(5-Cyano-1-ethyl-3-indolyl)-cyclohexanone
Reaktionsgleichung
C(C1C=C2C(=CC=1)N(C)C=C2C1CCC(=O)CC1)#N.O1[C:24]2([CH2:29][CH2:28][CH:27]([C:30]3[C:38]4[C:33](=[CH:34][CH:35]=[C:36]([C:39]#[N:40])[CH:37]=4)[N:32]([CH2:41][CH3:42])[CH:31]=3)[CH2:26][CH2:25]2)[O:23]CC1>>[C:39]([C:36]1[CH:37]=[C:38]2[C:33](=[CH:34][CH:35]=1)[N:32]([CH2:41][CH3:42])[CH:31]=[C:30]2[CH:27]1[CH2:28][CH2:29][C:24](=[O:23])[CH2:25][CH2:26]1)#[N:40]Komponenten
3
Versuchsvorschrift
This compound was prepared in the manner described above for intermediate 6a by replacing 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-5-cyano-1-methyl-indole with 3-(1,4-dioxa-spiro[4,5]-dec-8-yl)-5-cyano-1-ethyl-indole (6.77 g, 22 mmol) to afford 4.33 g (75%) of the title compound as a white solid: mp 124° C.
Aufarbeitung
- customThis compound was prepared in the manner