HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → 3-(3-Benzyl-3h-imidazol-4-yl)-1-(4-isobutylphenyl)-propen-1-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | 4'-Isobutylacetophenone | HCID 93214 | — |
| Edukt | 1-Benzyl-1H-imidazole-5-carboxaldehyde | HCID 2773239 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 3-(3-Benzyl-3h-imidazol-4-yl)-1-(4-isobutylphenyl)-propen-1-one | HCID 53707934 | — |
Reaktionsschritte
A solution of 4-isobutylacetophenone (2.0 g), 3-benzyl-3H-imidazole-4-carbaldehyde (2.1 g) and 48% sodium hydroxide (0.65 ml) in methanol (20 ml) is heated at 55-60° C. for 6 hours. The reaction mixture is then cooled in an ice bath. The resulting precipitate is filtered, and rinsed with methanol. The yield is 2.5 g.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06313311B1 |
| Quelldatensatz | uspto-grants-2001_11 |
| ORD ID | ord-9e7a0ec4bf914fee8868b8b03475f04f |
| Quellennotiz | uspto-grants-2001_11 |