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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 4298Erstellt: 24. Oktober 2026

Methyl iodide → 8-(2-Chlorobenzyloxy)-3-trimethylammoniomethyl-2-methylimidazo[1,2-a]pyridine iodide

https://huagongshe.com/de/reaction/4298

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethyl iodideHCID 6328—
Edukt8-(2-Chlorobenzyloxy)-3-dimethylaminomethyl-2-methylimidazo[1,2-a]pyridineHCID 13825936—
LösungsmittelAcetoneHCID 180—
Produkt8-(2-Chlorobenzyloxy)-3-trimethylammoniomethyl-2-methylimidazo[1,2-a]pyridine iodideHCID 13825937101,7%

Reaktionsschritte

Methyl iodide (3.48 g) was added dropwise to a solution of 8-(2-chlorobenzyloxy)-3-dimethylaminomethyl-2-methylimidazo[1,2-a]pyridine (7.8 g) in acetone (100 ml) at room temperature and the mixture was stirred for 24 hours. The resulting precipitate was collected by filtration, washed with acetone, and dried in a desiccator to give 8-(2-chlorobenzyloxy)-3-trimethylammoniomethyl-2-methylimidazo[1,2-a]pyridine iodide (11.35 g).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04725601
Quelldatensatzuspto-grants-1988_02
ORD IDord-91c2eee7c15b45b0a59d06a37df37e76
Quellennotizuspto-grants-1988_02