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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 431203Erstellt: 25. Oktober 2026

2-Aminothiazole → (2,6-Dimethyl-phenyl)-(6-pyridin-4-yl-imidazo[2,1-b]thiazol-5-yl)-amine

https://huagongshe.com/reaction/431203

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-AminothiazoleHCID 2155—
Edukt4-PyridinecarboxaldehydeHCID 13389—
Edukt2,6-Dimethylphenyl isocyanideHCID 76009—
LösungsmittelPerchloric AcidHCID 24247—
Produkt(2,6-Dimethyl-phenyl)-(6-pyridin-4-yl-imidazo[2,1-b]thiazol-5-yl)-amineHCID 22335557—

Reaktionsschritte

Compound 21 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 2-aminothiazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) 2,6-dimethylphenylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 4-pyridinecarbaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06657064B2
Quelldatensatzuspto-grants-2003_12
ORD IDord-f6405ee748aa444082c3473abc29cd5b
Quellennotizuspto-grants-2003_12