Acetyl chloride → N-Butyl-N-[6-(4-tert-butyl-phenyl)-2-methyl-imidazo[2,1-b]thiazol-5-yl]-acetamide

Beteiligte Stoffe

Reaktionsschritte

Compound 56 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 2-amino-5-methylthiazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) n-butylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 4-tert-butylbenzaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) and by reaction with acetyl chloride, the excess acetyl chloride being removed in vacuo.

Herkunft & Nachweise