Phosphorus oxychloride → HCID 11196721, Verbindung

HRID 431591

Reaktionsgleichung

Reaktionsgleichung von HRID 431591
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:17]=[C:16](O)[C:15]3[CH2:14][CH2:13][CH2:12][CH2:11][C:10]=3[N:9]=2)=[CH:4][CH:3]=1.P(Cl)(Cl)([Cl:21])=O>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:17]=[C:16]([Cl:21])[C:15]3[CH2:14][CH2:13][CH2:12][CH2:11][C:10]=3[N:9]=2)=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 24813Phosphorus oxychlorideHCID 178517489HCID 178517489, Verbindung

Produkt 1

HCID 11196721HCID 11196721, Verbindung

Versuchsvorschrift

8.0 g of 2-(4-chlorophenyl)4-hydroxy-5,6,7,8-tetrahydroquinazoline were heated to 100° C. in 10 ml of phosphorus oxychloride. After 3 hours, the cooled solution was carefully poured onto ice water. The crystalline product was filtered off with suction, washed well with water and dried in vacuo at room temperature. Yield: 6.2 g; m.p.: 121° C.

Aufarbeitung

  1. additionthe cooled solution was carefully poured onto ice water
  2. filtrationThe crystalline product was filtered off with suction
  3. washwashed well with water
  4. customdried in vacuo at room temperature

Quellen und Nachweise

ORD-Eintrag
ord-8f8fbe9ac0ba485ab79f927629ac50de
Quelldatensatz
uspto-grants-2003_12
Patentnummer
US06660746B1

Verknüpfte Notizen

Wird geladen…