HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N,N-bis(3-aminopropyl)methylamine → 1-{3-[4-(3-Aminopropyl)piperazin-1-yl]propyl}amino-7-fluoro-4-nitro-10H-acridin-9-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N,N-bis(3-aminopropyl)methylamine | HCID 7777 | — |
| Edukt | 1,4-Piperazinediethylamine | HCID 81020 | — |
| Edukt | 1-{2-[4-(2-aminoethyl)piperazin-1-yl]ethyl}amino-7-fluoro-4-nitro-10H-acridin-9-one | HCID 18760220 | — |
| Edukt | 1-{3-[methyl(3-aminopropyl)amino]propyl}amino-7-fluoro-4-nitro-10H-acridin-9-one | HCID 18760222 | — |
| Produkt | 1-{3-[4-(3-Aminopropyl)piperazin-1-yl]propyl}amino-7-fluoro-4-nitro-10H-acridin-9-one | HCID 18760212 | — |
Reaktionsschritte
Beginning with N,N-bis(3 -aminopropyl)methylamine, 1-{3-[methyl(3-aminopropyl)amino]propyl}amino-7-fluoro-4-nitro-10H-acridin-9-one (compound 2c) is prepared by the above method. By the same method, but beginning with 1,4-bis(2-aminoethyl)piperazine, it is possible to prepare 1-{2-[4-(2-aminoethyl)piperazin-1-yl]ethyl}amino-7-fluoro-4-nitro-10H-acridin-9-one.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06664263B2 |
| Quelldatensatz | uspto-grants-2003_12 |
| ORD ID | ord-c6b2c0ee5770403cb5b7b0800cd572fa |
| Quellennotiz | uspto-grants-2003_12 |