1-Butanol → n-Butyl 1-benzoyl-3-piperidinecarboxylate

Beteiligte Stoffe

Reaktionsschritte

The reaction was run in the same manner as ethyl 1-(3-thiophenecarbonyl)-3-piperidinecarboxylate, starting with 1-benzoyl-3-piperidine carboxylic acid (500 mg; 2.1 mmol) and commercially available n-butanol (500 μl; 5.5 mmol). The crude product was distilled at 225° C./0.1 torr, giving n-butyl 1-benzoyl-3-piperidinecarboxylate (258.2 mg) as a light yellow oil. MS m/z (positive ion) 312 (M+Na+; 75), 290 (NH+; 100).

Herkunft & Nachweise