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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 433210Erstellt: 24. Oktober 2026

Cyclohexene → 5-[3-(4-Aminophenyl)propyl]-3-(4-fluorophenyl)-1-methyl-4-(4-pyridyl)pyrazole

https://huagongshe.com/de/reaction/433210

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktCyclohexeneHCID 8079—
Edukt5-[3-(4-Nitrophenyl)propyl]-3-(4-fluorophenyl)-1-methyl-4-(4-pyridyl)pyrazoleHCID 21992365—
KatalysatorHCID 178418390HCID 178418390—
LösungsmittelMethanolHCID 887—
Produkt5-[3-(4-Aminophenyl)propyl]-3-(4-fluorophenyl)-1-methyl-4-(4-pyridyl)pyrazoleHCID 21992411103%

Reaktionsschritte

45 mg of 5-[3-(4-nitrophenyl)propyl]-3-(4-fluorophenyl)-1-methyl-4-(4-pyridyl)pyrazole was dissolved in 6 ml of methanol, followed by the addition of 2 ml of cyclohexene. Then, 45 mg of 10% palladium-carbon was added thereto, followed by heating under reflux for 2 hours. After the reaction mixture was filtered, the filtrated was concentrated to obtain 43 mg of the title compound quantitatively as a colorless amorphous substance.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06667325B1
Quelldatensatzuspto-grants-2003_12
ORD IDord-99a25547c541488bb125ae499f30bf06
Quellennotizuspto-grants-2003_12