4-(Trifluoromethyl)aniline → 1-Boc-4-(4-Trifluoromethyl-phenylamino)-piperidine

HRID 43349Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 43349
O=[C:2]1[CH2:7][CH2:6][N:5]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[CH2:4][CH2:3]1.[F:15][C:16]([F:25])([F:24])[C:17]1[CH:23]=[CH:22][C:20]([NH2:21])=[CH:19][CH:18]=1>>[F:15][C:16]([F:24])([F:25])[C:17]1[CH:18]=[CH:19][C:20]([NH:21][CH:2]2[CH2:7][CH2:6][N:5]([C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[CH2:4][CH2:3]2)=[CH:22][CH:23]=1

Komponenten

3

Edukt 2

HCID 99644-(Trifluoromethyl)anilineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Produkt 1

HCID 220291421-Boc-4-(4-Trifluoromethyl-phenylamino)-piperidine

Versuchsvorschrift

The title compound was prepared from 1,1-dimethylethyl 4-oxo-1-piperidinecarboxylate and 4-trifluoromethylaniline using a method similar to that described for D20

Quellen und Nachweise

ORD-Eintrag
ord-0cdf9bad8f684c969d72ef5d723d76a0
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08536182B2

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