3-(Methylthio)phenylacetic acid → N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

HRID 433534Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 433534
[CH3:1][S:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]([OH:12])=O)[CH:6]=[CH:7][CH:8]=1.[CH2:13]([O:17][C:18](=[O:22])[C@H:19]([CH3:21])[NH2:20])[CH:14]([CH3:16])[CH3:15]>>[CH2:13]([O:17][C:18](=[O:22])[C@H:19]([CH3:21])[NH:20][C:10](=[O:12])[CH2:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([S:2][CH3:1])[CH:4]=1)[CH:14]([CH3:16])[CH3:15]

Komponenten

3

Edukt 2

HCID 27374613-(Methylthio)phenylacetic acidHCID 137435562-methylpropyl (2S)-2-aminopropanoate

Produkt 1

HCID 15481777N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

Versuchsvorschrift

Following General Procedure BI above, and using 3-methylthiophenylacetic acid (CAS# 18698-73-2) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Aufarbeitung

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

Quellen und Nachweise

ORD-Eintrag
ord-099ca1db81bb4de18634f3edd061deab
Quelldatensatz
uspto-grants-2003_12
Patentnummer
US06667305B1

Notizen zur Reaktion

Wird geladen…