HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole → 5-Ethyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole | HCID 68406043 | — |
| Lösungsmittel | Sulfuric Acid | HCID 1118 | — |
| Produkt | 5-Ethyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde | HCID 86648487 | 29,1% |
Reaktionsschritte
The same operation as in Example (33b) was performed using 2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole obtained in Example (39c) (about 4.09 mmol) and 2 N sulfuric acid (30 mL), to obtain 228.3 mg of the title compound as a white solid (29%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08536197B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-c2732bdc31d840f1a6f62f8d8476e4c5 |
| Quellennotiz | uspto-grants-2013_09 |