Methyl bromoacetate → 3-Bromo-2-methoxyphenoxyacetic acid methyl ester

HRID 435507Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 435507
[Br:1][C:2]1[C:3]([O:9][CH3:10])=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.Br[CH2:12][C:13]([O:15][CH3:16])=[O:14]>>[CH3:16][O:15][C:13](=[O:14])[CH2:12][O:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Br:1])[C:3]=1[O:9][CH3:10]

Komponenten

3

Edukt 2

HCID 60984Methyl bromoacetateHCID 218775343-Bromo-2-methoxyphenol

Produkt 1

HCID 541832043-Bromo-2-methoxyphenoxyacetic acid methyl ester

Versuchsvorschrift

The compound of Formula XVIII wherein s is zero can also be prepared by treating 3-bromo-2-methoxyphenol with methyl bromoacetate to give 3-bromo-2-methoxyphenoxyacetic acid methyl ester which is reduced to the alcohol using, e.g., diisobutylaluminum hydride with subsequent protection of the alcohol with an R12 protecting group as generally described hereinbefore.

Aufarbeitung

  1. customcan also be prepared

Quellen und Nachweise

ORD-Eintrag
ord-992ba6eabc2d43408cdc5486d3186ed8
Quelldatensatz
uspto-grants-1983_08
Patentnummer
US04401824

Notizen zur Reaktion

Wird geladen…