2-Pentanone → 1-Bromo-trans-1-octen-3-one

HRID 436094

Reaktionsgleichung

Reaktionsgleichung von HRID 436094
Cl/[CH:2]=[CH:3]/[C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[Br-:11].[Li+].CC(=O)CCC>>[Br:11]/[CH:2]=[CH:3]/[C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

Komponenten

4

Edukt 3

HCID 78952-PentanoneHCID 82050Lithium BromideHCID 110410031-Chloro-trans-1-octen-3-one

Produkt 1

HCID 117903381-Bromo-trans-1-octen-3-one

Versuchsvorschrift

A mixture of 68.0 g. (0.424 mole) of 1-chloro-trans-1-octen-3 one (Example 723) and 444 g. (4.24 moles) of anhydrous lithium bromide in 900 ml. of 2-pentanone is refluxed for 30 minutes, cooled, and partitioned between ice water and either. The organic phase is washed with water and saturated brine, dried (NaSO4), and evaporated to an oil. This material is used directly without purification.

Aufarbeitung

  1. additionA mixture of 68.0 g
  2. temperaturecooled
  3. custompartitioned between ice water
  4. washThe organic phase is washed with water and saturated brine
  5. dry with materialdried (NaSO4)
  6. customevaporated to an oil
  7. customThis material is used directly without purification

Quellen und Nachweise

ORD-Eintrag
ord-84057573e3f74320bbd6ddedd7ba4a9f
Quelldatensatz
uspto-grants-1977_02
Patentnummer
US04007210

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