2-Methylcinnamic aldehyde → HCID 57311439, Verbindung

HRID 436444

Reaktionsgleichung

Reaktionsgleichung von HRID 436444
Cl.[NH:2]([C:4]1[C:13]2[C:8](=[CH:9][C:10]([O:16][CH3:17])=[C:11]([O:14][CH3:15])[CH:12]=2)[CH2:7][CH2:6][N:5]=1)[NH2:3].[CH3:18][C:19](=[CH:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH:20]=O.C(O)C.CO>C(O)C.O>[CH3:18][C:19](=[CH:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH:20]=[N:3][NH:2][C:4]1[C:13]2[C:8](=[CH:9][C:10]([O:16][CH3:17])=[C:11]([O:14][CH3:15])[CH:12]=2)[CH2:7][CH2:6][N:5]=1

Komponenten

5

Edukt 3

HCID 75572-Methylcinnamic aldehydeHCID 18681192Ethanol, mixt. with methanolHCID 681224371-Hydrazinyl-6,7-dimethoxy-3,4-dihydroisoquinoline--hydrogen chloride (1/1)

Produkt 1

HCID 57311439HCID 57311439, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 19096565Water ethanolLösungsmittel

Versuchsvorschrift

In a manner similar to that of Example 18 condensation of 1-hydrazino-6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride (9 g.) and α-methylcinnamaldehyde (5.62 g.) and recrystallization of the resulting product first from ethanol-methanol and then from ethanol-water afforded 1-[2-(2-methyl-3-phenylallylidene)hydrazino]-6,7-dimethoxy-3,4-dihydroisoquinoline (I: X= C6H5CH=C(CH3), X' = Y = Y' = H, Z = Z' = CH3O) hydrochloride monohydrate (10.2 g., m.p. 215°-217° C.).

Quellen und Nachweise

ORD-Eintrag
ord-896d0be707374c48b9f093b7f4b65ce5
Quelldatensatz
uspto-grants-1977_02
Patentnummer
US04009170

Verknüpfte Notizen

Wird geladen…