Benzyl 2-amino-2-methylpropanoate → Glycyl-alpha-aminoisobutyric acid benzyl ester hydrochloride
Reaktionsgleichung
[CH2:1]([O:8][C:9](=[O:14])[C:10]([NH2:13])([CH3:12])[CH3:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:15].C([O:23][C:24](=O)[C@H:25](C)[NH:26]C(=O)CN)C1C=CC=CC=1>>[ClH:15].[CH2:1]([O:8][C:9](=[O:14])[C:10]([NH2:13])([CH3:11])[CH2:12][C:24](=[O:23])[CH2:25][NH2:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
substitution of an equivalent amount of α-aminoisobutyric acid benzyl ester for the L-alanine benzyl ester of Example 3, and substantial repetition of the procedure detailed therein, affords glycyl-α-aminoisobutyric acid benzyl ester hydrochloride.
Quellen und Nachweise
- ORD-Eintrag
- ord-24f0480a8e4d4c39b3420989f1915ec2
- Quelldatensatz
- uspto-grants-1977_06