Ethyl Acetate → HCID 11148694, Verbindung

HRID 437520Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 437520
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][NH:11][C:12](=[O:17])[C:13]([F:16])([F:15])[F:14])=[CH:6][CH:5]=1)([O-])=O.C(OCC)(=O)C.[H][H]>C(O)C.[Pt]=O>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:10][NH:11][C:12](=[O:17])[C:13]([F:14])([F:15])[F:16])=[CH:8][CH:9]=1

Komponenten

6

Edukt 3

HCID 8857Ethyl AcetateHCID 31126762,2,2-trifluoro-N'-(4-nitrophenyl)acetohydrazideHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 11148694HCID 11148694, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

2-(4-Nitrophenyl)-1-trifluoroacetylhydrazine (2.5 g, 0.01 mole) and platinum oxide (84%, catalytic amount) were mixed in ethanol (100 ml) and ethyl acetate (100 ml) in a Parr shaker bottle. The reaction mixture was hydrogenated at room temperature until hydrogen uptake ceased. The reaction mixture was filtered and the solvent was evaporated from the filtrate leaving a brown semisolid. Yield 2.0 g (91%), no m.p. was taken on this material. Spectral data verified its structure.

Aufarbeitung

  1. filtrationThe reaction mixture was filtered
  2. customthe solvent was evaporated from the filtrate
  3. customleaving a brown semisolid

Quellen und Nachweise

ORD-Eintrag
ord-74e039caf05840cb80fe06a5c4baa469
Quelldatensatz
uspto-grants-1977_06
Patentnummer
US04031127

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