HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)benzoate → Methyl cis(+/-)-3-(4-amino-3-methoxypiperidin-1-yl)benzoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)benzoate | HCID 86648495 | — |
| Katalysator | HCID 178418390 | HCID 178418390 | — |
| Produkt | Methyl cis(+/-)-3-(4-amino-3-methoxypiperidin-1-yl)benzoate | HCID 86648708 | 87,5% |
Reaktionsschritte
The same operation as in Example (160c) was performed using methyl cis(±)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)benzoate obtained in Example (42a) (180 mg) and a 10% palladium-carbon catalyst (150 mg), to obtain 104.5 mg of the title compound as a white solid. The resulting compound was used for the next reaction without purification.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08536197B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-e4d7c9fea97e43ada9361d3a3512a57a |
| Quellennotiz | uspto-grants-2013_09 |