Phosgeniminium chloride → N'-(4-cyano-3-propyl-5-isothiazolyl)-N,N-dimethylchloroformamidine

Beteiligte Stoffe

Reaktionsschritte

In the manner of Example VI, a solution of 8.4 g of 5-amino-4-cyano-3-propylisothiazole in 50 ml of dichloromethane was treated with 9.8 g of N-(dichloromethylene)-N,N-dimethylammonium chloride. After removal of the volatile materials under reduced pressure, the residue was recrystallized from 90:10 hexane:benzene to yield 6.5 g of N'-(4-cyano-3-propyl-5-isothiazolyl)-N,N-dimethylchloroformamidine, mp 108°-109°. The ir and nmr spectra were consistent with the assigned structure.

Herkunft & Nachweise