Phosgeniminium chloride → HCID 54107383, Verbindung

HRID 437717

Reaktionsgleichung

Reaktionsgleichung von HRID 437717
[NH2:1][C:2]1[S:6][N:5]=[C:4]([C:7]([CH3:10])([CH3:9])[CH3:8])[C:3]=1[C:11]#[N:12].[Cl-].[Cl:14][C:15](Cl)=[N+:16]([CH3:18])[CH3:17]>ClCCl>[C:7]([C:4]1[C:3]([C:11]#[N:12])=[C:2]([N:1]=[C:15]([Cl:14])[N:16]([CH3:18])[CH3:17])[S:6][N:5]=1)([CH3:9])([CH3:8])[CH3:10]

Komponenten

4

Edukt 2

HCID 2723945Phosgeniminium chlorideHCID 214267415-Amino-3-(1,1-dimethylethyl)-4-isothiazolecarbonitrile

Produkt 1

HCID 54107383HCID 54107383, VerbindungAusbeute 67,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

In the manner of Example VI, 9.1 g of 5-amino-3-tert-butyl- 4-cyanoisothiazole and 9.8 g of N-(dichloromethylene)-N,N-dimethylammonium chloride were allowed to react in 50 ml of dichloromethane. The volatile materials were evaporated under reduced pressure. The residue was recrystallized from hexane to give 9.2 g of N'-(3-tert-butyl-4 -cyano-5-isothiazolyl)-N,N-dimethylchloroformamidine, mp 94°-100°. The ir and nmr spectra were consistent with the assigned structures.

Aufarbeitung

  1. customThe volatile materials were evaporated under reduced pressure
  2. customThe residue was recrystallized from hexane

Quellen und Nachweise

ORD-Eintrag
ord-1504d35d190a4cb181d6e756db393ccc
Quelldatensatz
uspto-grants-1977_06
Patentnummer
US04032322

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