Phosgeniminium chloride → HCID 54431897, Verbindung

HRID 437719

Reaktionsgleichung

Reaktionsgleichung von HRID 437719
[NH2:1][C:2]1[S:6][N:5]=[C:4]([CH2:7][CH3:8])[C:3]=1[C:9]#[N:10].[Cl-].[Cl:12][C:13](Cl)=[N+:14]([CH3:16])[CH3:15]>ClCCl>[C:9]([C:3]1[C:4]([CH2:7][CH3:8])=[N:5][S:6][C:2]=1[N:1]=[C:13]([Cl:12])[N:14]([CH3:16])[CH3:15])#[N:10]

Komponenten

4

Edukt 2

HCID 2723945Phosgeniminium chlorideHCID 21426744HCID 21426744, Verbindung

Produkt 1

HCID 54431897HCID 54431897, VerbindungAusbeute 16,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

In the manner of Example VI, 7.6 g of 5-amino-4 -cyano-3-ethylisothiazole and 8.1 g of N-(dichloromethylene) -N,N-dimethylammonium chloride were allowed to react in 100 ml of dichloromethane. The volatile materials were evaporated under reduced pressure. The residue was recrystallized twice from cyclohexane to give 2.0 g of N'-(4-cyano-3-ethyl-5-isothiazolyl)-N,N-dimethylchloroformamidine, mp 95°-97°. The nmr spectrum was consistent with the assigned structure.

Aufarbeitung

  1. customThe volatile materials were evaporated under reduced pressure
  2. customThe residue was recrystallized twice from cyclohexane

Quellen und Nachweise

ORD-Eintrag
ord-a72d35e7189c43719183e11077ed6902
Quelldatensatz
uspto-grants-1977_06
Patentnummer
US04032322

Verknüpfte Notizen

Wird geladen…