2-(Trifluoromethyl)benzoic acid → 2-(Trifluoromethyl)benzoyl chloride

HRID 439961

Reaktionsgleichung

Reaktionsgleichung von HRID 439961
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:11]=[CH:10][CH:9]=[CH:8][C:4]=1[C:5](O)=[O:6].S(Cl)([Cl:16])=O>>[F:1][C:2]([F:13])([F:12])[C:3]1[CH:11]=[CH:10][CH:9]=[CH:8][C:4]=1[C:5]([Cl:16])=[O:6]

Komponenten

3

Edukt 2

HCID 98992-(Trifluoromethyl)benzoic acidHCID 24386Thionyl Chloride

Produkt 1

HCID 675612-(Trifluoromethyl)benzoyl chloride

Versuchsvorschrift

A solution of 2.0 g of o-trifluoromethylbenzoic acid in 21 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is concentrated from toluene three times and dried under vacuum to give 2.1 g of the desired product as a residue.

Aufarbeitung

  1. temperatureat reflux for 1 hour
  2. customThe volatiles are evaporated in vacuo
  3. customto give a residue which
  4. concentrationis concentrated from toluene three times
  5. customdried under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-0964e346b3a7495f8fa90577a328961c
Quelldatensatz
uspto-grants-1996_05
Patentnummer
US05516774

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