Thionyl Chloride → 6-(2-Thienyl)pyridine-3-carbonyl chloride

Beteiligte Stoffe

Reaktionsschritte

A mixture of 1.8 g of 6-(2-thienyl)pyridine-3-carboxylic acid in 50 ml of thionyl chloride is refluxed under dry conditions for 1 hour. The reaction mixture is evaporated to dryness and evaporated again from 50 ml of carbon tetrachloride to a residue. The residue is dissolved in 60 ml of methylene chloride and used further reactions.

Herkunft & Nachweise