Toluene → Toluene dimethoxyethane

A saturated solution of compound of formula (I), Form VI in 1,2-dimethoxyethane was made at room temperature by adding 1.4 mL of 1,2-dimethoxyethane to approximately 698 mg of Form VI. The saturated solution was stirred for approximately 1 h and subsequently filtered through a filter of 0.45 μm pore size. A reverse addition of 200 μL of the as prepared saturated solution was added at once to 800 μL of toluene acting as anti-solvent. After precipitation the solid material was separated from solution and analyzed as described in Table 1. No drying under vacuum was applied prior to the analyses.

1. customwas made at room temperature
2. filtrationsubsequently filtered through
3. filtrationa filter of 0.45 μm pore size
4. additionA reverse addition of 200 μL of the
5. customas prepared saturated solution
6. customAfter precipitation the solid material
7. customwas separated from solution

ORD-Eintrag

ord-0ee8d7016dc64ec9aad86f2e6a651708

Quelldatensatz

uspto-grants-2013_09

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US08541391B2