Diethylaminopropyl chloride, hydrochloride → Hydrochloric Acid

HRID 443745Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 443745
Br[C:2]1[C:3]2[C:4]3[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]=3[CH:12]=[CH:13][CH:14]=2.Cl.[CH2:16]([N:18]([CH2:23][CH3:24])[CH2:19][CH2:20][CH2:21][Cl:22])[CH3:17]>>[CH2:16]([N:18]([CH2:23][CH3:24])[CH2:19][CH2:20][CH2:21][N:7]1[C:8]2[C:4]3[C:3](=[CH:14][CH:13]=[CH:12][C:5]=3[C:6]1=[O:11])[CH:2]=[CH:10][CH:9]=2)[CH3:17].[ClH:22]

Komponenten

4

Edukt 2

HCID 145749Diethylaminopropyl chloride, hydrochlorideHCID 7547635-Bromo-8-naphtholactam

Produkt 2

HCID 313Hydrochloric AcidHCID 23465277HCID 23465277, Verbindung

Versuchsvorschrift

By the procedure described for Compound I, 6-bromobenz[cd]indol-2(1H)-one and 3-diethylaminopropyl chloride hydrochloride yield 6-bromo-1-(3-diethylaminopropylbenz[cd]-indol-2 (1H)-one (Ie), HCl salt, mp. 183°-185° C., while 3-dimethylaminopropyl chloride hydrochloride yields 6bromo-1-(3-dimethylaminopropyl) benz[cd]-2(1H)-one (If), HCl salt, mp. 264°-267° C. Similarly, 6-chlorobenz[cd]indol-2(1H)-one and methyl iodide yield 6-chloro-1-methylbenz[cd]-2(1H)-one (Ig), while benz[cd]indol-2(1H)-one and 4-chlorobenzyl chloride yield 1-(4-chlorobenzyl)benz[cd]indol-2(1H)-one (Ih), mp. 128°-129.5° C.

Quellen und Nachweise

ORD-Eintrag
ord-93e9498da06a4ae9860b95fbd3730a0c
Quelldatensatz
uspto-grants-1981_04
Patentnummer
US04261896

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