1,3-Dichloroacetone → HCID 86736622, Verbindung

HRID 444007Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 444007
[Cl:1][CH2:2][C:3]([CH2:5]Cl)=O.[CH2:7]([NH:11][C:12]([NH:14][C:15]([NH2:17])=[S:16])=[NH:13])[CH2:8][CH2:9][CH3:10]>CC(C)=O>[ClH:1].[CH2:7]([N:11]=[C:12]([NH2:13])[NH:14][C:15]1[S:16][CH:5]=[C:3]([CH2:2][Cl:1])[N:17]=1)[CH2:8][CH2:9][CH3:10]

Komponenten

4

Edukt 2

HCID 107931,3-DichloroacetoneHCID 178449223HCID 178449223, Verbindung

Produkt 1

HCID 86736622HCID 86736622, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel2×

Versuchsvorschrift

A solution of 1,3-dichloroacetone (3.02 g.) in acetone (10 ml.) was added to a stirred suspension of (N-n-butylamidino)thiourea (4.04 g.) in acetone (25 ml.) at room temperature. The resulting clear pale yellow solution was stirred for three days, then cooled in ice, and the precipitated solid filtered off and washed with acetone to give 2-(2-n-butylguanidino)-4-chloromethylthiazole hydrochloride.

Aufarbeitung

  1. temperaturecooled in ice
  2. filtrationthe precipitated solid filtered off
  3. washwashed with acetone

Quellen und Nachweise

ORD-Eintrag
ord-84086ea8dd454f728c4a0af36eb519fc
Quelldatensatz
uspto-grants-1981_04
Patentnummer
US04262126

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