Nitrourea → Diethyl 2-(3-hydroxy-3-(p-biphenylyl)-propylamino)nonanedioate

HRID 444036

Reaktionsgleichung

Reaktionsgleichung von HRID 444036
[O:1]=[C:2]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)[CH2:3][CH2:4][NH:5][CH:6]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:7]([O:9][CH2:10][CH3:11])=[O:8].C(C(C=C)=O)=C.[N+](NC(N)=O)([O-])=O>C(O)C>[OH:1][CH:2]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[C:29]1[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=1)[CH2:3][CH2:4][NH:5][CH:6]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:7]([O:9][CH2:10][CH3:11])=[O:8]

Komponenten

5

Edukt 3

HCID 62372NitroureaHCID 5431991,4-Pentadien-3-oneHCID 70578184Diethyl 2-(3-oxo-3-(p-biphenylyl)propylamino)nonanedioate

Produkt 1

HCID 70510532Diethyl 2-(3-hydroxy-3-(p-biphenylyl)-propylamino)nonanedioate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of diethyl 2-(3-hydroxy-3-(p-biphenylyl)-propylamino)nonanedioate (5 g), which was prepared via diethyl 2-(3-oxo-3-(p-biphenylyl)propylamino)nonanedioate from the appropriate vinyl ketone using the procedure of Example 2, in absolute ethanol (20 ml) was heated at 60° while nitrourea (1.12 g) was added portion-by-portion.

Aufarbeitung

  1. additionwas added portion-by-portion

Quellen und Nachweise

ORD-Eintrag
ord-7d53ce85b93c416e9ea091733dd1cfec
Quelldatensatz
uspto-grants-1981_04
Patentnummer
US04262128

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