Ammonia → 2,3-Dihydro-3,3-dimethylbenzofuran-5-carboxylic acid amide
Reaktionsgleichung
[CH3:1][C:2]1([CH3:14])[C:6]2[CH:7]=[C:8]([C:11](Cl)=[O:12])[CH:9]=[CH:10][C:5]=2[O:4][CH2:3]1.[NH3:15]>>[CH3:1][C:2]1([CH3:14])[C:6]2[CH:7]=[C:8]([C:11]([NH2:15])=[O:12])[CH:9]=[CH:10][C:5]=2[O:4][CH2:3]1Komponenten
3
Versuchsvorschrift
The product of stage (b) (4.2 g) was added dropwise to excess aqueous ammonia with stirring and ice cooling. After 1 hour the white precipitate was filtered off and recrystallised from ethanol to give 1.1 g of title product, mp 136°-138° C.
Aufarbeitung
- filtrationAfter 1 hour the white precipitate was filtered off
- customrecrystallised from ethanol
Quellen und Nachweise
- ORD-Eintrag
- ord-c9111588a20349739d8406f5176bc31e
- Quelldatensatz
- uspto-grants-1981_04
- Patentnummer
- US04263037
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