Acefylline → N-[2-(4-Cyanophenyl)-ethyl]-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)acetamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Acefylline	HCID 69550	—
Edukt	4-(2-Aminoethyl)benzonitrile	HCID 21912525	—
Produkt	N-[2-(4-Cyanophenyl)-ethyl]-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)acetamide	HCID 59205118	21,2%

Reaktionsschritte

Compound 409 (93 mg, 21%) was prepared from 101 (300 mg, 1.3 mmol) and 115 (175 mg, 1.2 mmol) according to General Procedure B. MS (APCI): m/z 367 [M+H]+. Anal. Calcd. for C18H18N6O3.0.04EtOAc.0.1H2O: C, 58.68; H, 5.02; N, 22.61. Found: C, 58.75; H, 5.01; N, 22.46.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08541423B2
Quelldatensatz	uspto-grants-2013_09
ORD ID	ord-043c58e87eac4d25821711ff7f9377e9
Quellennotiz	uspto-grants-2013_09