Hydrochloric Acid → 4-Ethoxy-7-methylcoumarin

HRID 444221

Reaktionsgleichung

Reaktionsgleichung von HRID 444221
Cl.[OH:2][C:3]1[C:12]2[C:7](=[CH:8][C:9]([CH3:13])=[CH:10][CH:11]=2)[O:6][C:5](=[O:14])[CH:4]=1.[CH2:15](O)[CH3:16]>>[CH2:15]([O:2][C:3]1[C:12]2[C:7](=[CH:8][C:9]([CH3:13])=[CH:10][CH:11]=2)[O:6][C:5](=[O:14])[CH:4]=1)[CH3:16]

Komponenten

4

Edukt 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 546853074-Hydroxy-7-methylcoumarin

Produkt 1

HCID 6889444-Ethoxy-7-methylcoumarinAusbeute 72 %

Versuchsvorschrift

Dry hydrogen chloride was passed through a solution of 4-hydroxy-7-methylcoumarin (14 g; 0.08 mole) in ethanol (300 ml) for 15 mins and the resulting solution was refluxed for 30 minutes. After cooling, the solvent was removed in vacuo and the residue recrystallized from ethanol to give 11.74 g (72%) of product of m.p. 142°-143° C.; (Found; C, 70.24; H, 5.95; C12H12O3 requires; C, 70.60; H, 5.88%).

Aufarbeitung

  1. temperaturethe resulting solution was refluxed for 30 minutes
  2. temperatureAfter cooling
  3. customthe solvent was removed in vacuo
  4. customthe residue recrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-ed20385ddde44873bbe343fb9dc39b19
Quelldatensatz
uspto-grants-1981_04
Patentnummer
US04263299

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