3-Methoxybenzaldehyde → 3-methoxy-beta-methylstyrene Oxide

HRID 444365

Reaktionsgleichung

Reaktionsgleichung von HRID 444365
[C:1]1([SH+]C2C=CC=CC=2)C=CC=C[CH:2]=1.[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH:19]=[O:20]>O1CCCC1>[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH:19]1[O:20][CH:1]1[CH3:2]

Komponenten

4

Edukt 2

HCID 115693-MethoxybenzaldehydeHCID 22290449Diphenylsulfonium

Produkt 1

HCID 204969033-methoxy-beta-methylstyrene Oxide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Reaktionsbedingungen

Temperatur
-78 °C

Versuchsvorschrift

To a -78° C. solution of diphenylsulfonium ethylide (1.0 mole) in tetrahydrofuran (one liter) is slowly added 3-methoxybenzaldehyde (1.0 mole). The reaction mixture is stirred at -78° C. for 3 hours and then allowed to warm to room temperature. It is then added to ether-water and the ether phase separated. The ether phase is washed with water, dried (MgSO4) and evaporated. Fractional distillation of the residue gives the title product.

Aufarbeitung

  1. customTo a -78° C.
  2. temperatureto warm to room temperature
  3. customthe ether phase separated
  4. washThe ether phase is washed with water
  5. dry with materialdried (MgSO4)
  6. customevaporated
  7. distillationFractional distillation of the residue

Quellen und Nachweise

ORD-Eintrag
ord-1d7ae9b0030a4f068941b947e29d6068
Quelldatensatz
uspto-grants-1981_04
Patentnummer
US04263438

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