HCID 86663435, Verbindung → HCID 86663437, Verbindung

HRID 446527Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 446527
O=[CH:2][CH2:3][O:4][CH2:5][CH2:6][C:7]([O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[O:8].[NH2:14][C:15]1[CH:20]=[CH:19][C:18]([C:21]([N:23]([CH3:36])[CH2:24][CH2:25][CH2:26][N:27]([CH3:35])[C:28](=[O:34])[O:29][C:30]([CH3:33])([CH3:32])[CH3:31])=[O:22])=[CH:17][CH:16]=1>>[C:30]([O:29][C:28]([N:27]([CH3:35])[CH2:26][CH2:25][CH2:24][N:23]([CH3:36])[C:21]([C:18]1[CH:19]=[CH:20][C:15]([NH:14][CH2:2][CH2:3][O:4][CH2:5][CH2:6][C:7]([O:9][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:8])=[CH:16][CH:17]=1)=[O:22])=[O:34])([CH3:32])([CH3:31])[CH3:33]

Komponenten

3

Edukt 2

HCID 86663435HCID 86663435, VerbindungHCID 86663438CHO-PEG1-COOtBu

Produkt 1

HCID 86663437HCID 86663437, VerbindungAusbeute 83 %

Versuchsvorschrift

The compound (87 mg, 0.461 mmol) obtained in Example 28b and the compound (150 mg, 0.461 mmol) obtained in Example 28d were used to give the title compound (188 mg; yield, 83%) as a colorless oily substance according to the method described in Example 18b.

Quellen und Nachweise

ORD-Eintrag
ord-9832baf92a62409fbd7d522ee9d048c3
Quelldatensatz
uspto-grants-2013_07
Patentnummer
US08476253B2

Notizen zur Reaktion

Wird geladen…