Hydrochloric Acid → (2R)-2-amino-N,N-dimethylpropanamide hydrochloride
Reaktionsgleichung
C(OC(=O)[NH:7][C@@H:8]([C:10](=[O:14])[N:11]([CH3:13])[CH3:12])[CH3:9])(C)(C)C.[ClH:16]>O1CCOCC1>[ClH:16].[NH2:7][C@H:8]([CH3:9])[C:10]([N:11]([CH3:13])[CH3:12])=[O:14]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
((R)-1-Dimethylcarbamoyl-ethyl)-carbamic acid tert-butyl ester (1.1 g, 5.1 mmol) was dissolved in 26 mL of cold 4M HCl in dioxane. After 1.5 h the reaction was evaporated to provide (R)-2-amino-N,N-dimethyl-propionamide hydrochloride which was used without further purification.
Aufarbeitung
- customAfter 1.5 h the reaction was evaporated
Quellen und Nachweise
- ORD-Eintrag
- ord-3f7e6a1103844b4395bf35bb14e51da2
- Quelldatensatz
- uspto-grants-2013_07
- Patentnummer
- US08481541B2
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