HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(R)-Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(cyclopentyl)amino)butanoate → (R)-methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(isopropyl)amino)butanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (R)-Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(cyclopentyl)amino)butanoate | HCID 58405447 | — |
| Lösungsmittel | Acetone | HCID 180 | — |
| Produkt | (R)-methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(isopropyl)amino)butanoate | HCID 59815009 | — |
Reaktionsschritte
Intermediate C-1 was prepared similarly to the synthetic methods used to prepare Intermediate A with the exception that acetone was used instead of cyclopentanone in the reductive amination step.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08541418B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-3fd893af0d6544c4821cd0d1f8d7b325 |
| Quellennotiz | uspto-grants-2013_09 |