HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Nitro-1H-indole-2-carboxylic acid propylamide → 5-Amino-1H-indole-2-carboxylic acid propylamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Nitro-1H-indole-2-carboxylic acid propylamide | HCID 67023975 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 5-Amino-1H-indole-2-carboxylic acid propylamide | HCID 62057141 | 95% |
Reaktionsschritte
To a solution of 5-nitro-1H-indole-2-carboxylic acid propylamide (2.94 g, 11.9 mmol) in EtOH (150 ml) a suspension of palladium on charcoal (10%, 1 g) in EtOH was added. The mixture was hydrogenated at atmospheric pressure. After filtration and removal of the solvents in vacuo the product was obtained as a yellow powder (2.46 mg, 95%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08486984B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-630127751cc1404dbcd018eddda7be57 |
| Quellennotiz | uspto-grants-2013_07 |