1-[6-(Hydroxymethyl)pyridin-2-yl]ethanone oxime → [6-(1-Aminoethyl)pyridin-2-yl]methanol

Beteiligte Stoffe

Reaktionsschritte

To a solution of 1.8 g of 1-[6-(hydroxymethyl)pyridin-2-yl]ethanone oxime in 36 ml of methanol was added 500 mg of 10% palladium-carbon (50% wet) under an argon atmosphere, followed by stifling for 7 hours under a hydrogen atmosphere. After filtration through Celite, the filtrate was evaporated under reduced pressure to obtain 1.5 g of [6-(1-aminoethyl)pyridin-2-yl]methanol.

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