1-Ethynylcyclohexene → 1-Cyclohex-1-enylethynyl-3-trifluoromethyl-benzene

Beteiligte Stoffe

Reaktionsschritte

This product was prepared from toluene-4-sulfonic acid 3-trifluoromethyl-phenyl ester and 1-ethynyl-cyclohexene following the general procedure for the Sonogashira cross-coupling process described above. Chromatography eluent: heptane; yield (106 mg, 85%); 1H NMR δ (CDCl3): 7.68 (s, 1H), 7.6-7.7.49 (m, 2H), 7.46-7.37 (m, 1H), 6.28 (m, 1H), 2.31-2.12 (m, 4H), 1.73-1.57 (m, 4H); LCMS m/z: 250.

Herkunft & Nachweise