HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Ethynylcyclohexene → 1-Cyclohex-1-enylethynyl-4-trifluoromethoxy-benzene
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Ethynylcyclohexene | HCID 79128 | — |
| Edukt | Toluene-4-sulfonic acid 4-trifluoromethoxy-phenyl ester | HCID 18424495 | — |
| Lösungsmittel | Heptane | HCID 8900 | — |
| Produkt | 1-Cyclohex-1-enylethynyl-4-trifluoromethoxy-benzene | HCID 25221725 | — |
Reaktionsschritte
This product was prepared from toluene-4-sulfonic acid 4-trifluoromethoxy-phenyl ester and 1-ethynyl-cyclohexene following the general procedure for the Sonogashira cross-coupling process described above. Chromatography eluent: heptane; yield (110 mg, 83%); 1H NMR δ (CDCl3): 7.41 (d, J=8.38 Hz, 2H), 7.21 (d, J=8.37 Hz, 2H), 6.28 (m, 1H), 2.17 (dm, 4H), 1.63 (dm, 4H); LCMS m/z: 266.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08487109B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-a443adc7d1514c58a3542ae3902bad31 |
| Quellennotiz | uspto-grants-2013_07 |