HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Acetoxyisobutyroyl chloride → 2-[2-[[3-(2,5-Difluorophenyl)-1-benzofuran-5-yl]carbonyl]hydrazino]-1,1-dimethyl-2-oxoethyl acetate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Acetoxyisobutyroyl chloride | HCID 123496 | — |
| Edukt | 3-(2,5-Difluorophenyl)-1-benzofuran-5-carbohydrazide | HCID 68664374 | — |
| Produkt | 2-[2-[[3-(2,5-Difluorophenyl)-1-benzofuran-5-yl]carbonyl]hydrazino]-1,1-dimethyl-2-oxoethyl acetate | HCID 68663113 | 85% |
Reaktionsschritte
In the same manner as in Reference Example 129 and using 3-(2,5-difluorophenyl)-1-benzofuran-5-carbohydrazide instead of 3-bromo-1-benzofuran-5-carbohydrazide and 2-chloro-1,1-dimethyl-2-oxoethyl acetate instead of (1S)-2-chloro-1-methyl-2-oxoethyl acetate, the title compound (yield 85%) was obtained as colorless crystals.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08492378B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-33743152b32443c492c7f9c3145b33ee |
| Quellennotiz | uspto-grants-2013_07 |