4-Methoxy-3-(trifluoromethyl)benzyl bromide → 6-[5-[[4-Methoxy-3-(trifluoromethyl)benzyl]thio]-1,3,4-oxadiazol-2-yl]quinoline
Reaktionsgleichung
[N:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11]3[O:15][C:14]([SH:16])=[N:13][N:12]=3)=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[CH3:17][O:18][C:19]1[CH:26]=[CH:25][C:22]([CH2:23]Br)=[CH:21][C:20]=1[C:27]([F:30])([F:29])[F:28]>>[CH3:17][O:18][C:19]1[CH:26]=[CH:25][C:22]([CH2:23][S:16][C:14]2[O:15][C:11]([C:7]3[CH:6]=[C:5]4[C:10](=[CH:9][CH:8]=3)[N:1]=[CH:2][CH:3]=[CH:4]4)=[N:12][N:13]=2)=[CH:21][C:20]=1[C:27]([F:28])([F:30])[F:29]Komponenten
3
Versuchsvorschrift
In the same manner as in Example 7 and using 5-(6-quinolyl)-1,3,4-oxadiazole-2-thiol instead of 5-(1H-indazol-5-yl)-1,3,4-oxadiazole-2-thiol and 4-methoxy-3-(trifluoromethyl)benzyl bromide instead of 3-(trifluoromethyl)benzyl chloride, the title compound (yield 74%) was obtained as colorless crystals.
Quellen und Nachweise
- ORD-Eintrag
- ord-75b00fcfe11b45d583afbfe00838f336